The Enzymatic α-N-Methylation of Histidine

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

(n,1,1,α)-Center Problem

Given a set  of  points in the plane and a constant ,-center problem is to find two closed disks which each covers the whole , the diameter of the bigger one is minimized, and the distance of the two centers is at least . Constrained -center problem is the -center problem in which the centers are forced to lie on a given line . In this paper, we first introduce -center problem and its constrain...

متن کامل

Enzymatic Synthesis of Anserine in Skeletal Muscle by N-Methylation of Carnosines

Anserine biosynthesis may occur in skeletal muscle by two and possibly three pathways: (a) condensation of l-methylhistidine with p-alanine (1, Z), (6) direct N-methylation of carnosine (3, 4), and, possibly, (c) P-alanyl transfer from carnosine to 1-methylhistidine (5). The relative importance of these various routes is unevaluated, although some studies in viva suggest that species difference...

متن کامل

Enzymatic aminoacylation of an eight-base-pair microhelix with histidine.

The major determinant for the identity of alanine tRNAs is a single base pair in the acceptor helix that is proximal to the site of amino acid attachment. A 7-base-pair microhelix that recreates the acceptor helix can be charged with alanine. No other examples of charging of small helices with specific amino acids have been reported, to our knowledge. We show here that a 13-base-pair and an 8-b...

متن کامل

The Enzymatic Methylation of Ribonucleic Acid and Deoxyribonucleic Acid. Vii. the Methylation of Ribonucleic Acid.

Preceding publications from this laboratory have shown that the methylation of soluble ribonucleic acid is catalyzed by at least six discrete enzymes (l-3) which have been purified from extracts of Escherichia coli W. Two of these enzyme preparations catalyze the formation of l-methylguanine residues in SRNA,1 while a third produces 7-methylguanine. The others catalyze the methylation of uracil...

متن کامل

INVESTIGATION OF METHYLATION OF TNF-Α GENE PROMOTER IN PATIENTS WITH TYPE 2 DIABETES

Background: Type II diabetes is a chronic inflammatory condition that is associated with a combination of genetic and environmental factors. Tumor necrosis factor alpha or TNF-α as an adipocyte cytokine, which affects the signaling pathway of insulin, can contribute to insulin resistance in type 2 diabetes patients. Considering the importance of epigenetic changes in multifactorial diseases, th...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1970

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)62649-3